Yes, it can be. While our bodies react to the effects of the treatment, the targeted area may feel tingly, warm, light, or even, in rare circumstances, painful for a short while. These sensations are the result of the movement of blood and bodily fluids, and are a sign that the treatment is working. The body is reacting; things are changing.
In a previous question, we used an analogy of traffic on a highway. Here, we’ll refer to it again: as the traffic congestion (i.e. inflammation/pain) starts to ease and budge, the traffic (i.e. blood/bodily fluids) begins to move. It’s slow at first (i.e. tingling or pain), but eventually gets moving smoothly down the highway as it should (i.e. return to normal functioning and/or pain relief).